GEOGRAPHIC ATROPHY
نویسندگان
چکیده
منابع مشابه
Geographic atrophy and cardiovascular disease.
We read with great interest the article by Fleckenstein et al. on the association of the diffuse-trickling (DT) phenotype of geographic atrophy (GA) with cardiovascular disease (CVD), with possible significance for choroidal vascular compromise. We wish to make the readership of IOVS aware that our group has published several relevant observations about the relation among reticular macular dise...
متن کاملChoroidal Round Hyporeflectivities in Geographic Atrophy
PURPOSE In geographic atrophy (GA), choroidal vessels typically appear on structural optical coherence tomography (OCT) as hyperreflective round areas with highly reflective borders. We observed that some GA eyes show choroidal round hyporeflectivities with highly reflective borders beneath the atrophy, and futher investigated the charcteristcs by comparing structural OCT, indocyanine green ang...
متن کاملGeographic atrophy phenotype identification by cluster analysis
BACKGROUND/AIMS To identify ocular phenotypes in patients with geographic atrophy secondary to age-related macular degeneration (GA) using a data-driven cluster analysis. METHODS This was a retrospective analysis of data from a prospective, natural history study of patients with GA who were followed for ≥6 months. Cluster analysis was used to identify subgroups within the population based on ...
متن کاملMast Cell-Derived Tryptase in Geographic Atrophy
Purpose Our previous study demonstrated significantly more degranulating mast cells (MCs) in choroids from subjects with age-related macular degeneration compared to aged controls. This study examined the immunolocalization of tryptase, the most abundant MC secretory granule-derived serine protease, in aged control eyes and eyes with geographic atrophy (GA). Methods Postmortem human eyes with...
متن کاملVitreoretinal interface changes in geographic atrophy.
PURPOSE Geographic atrophy (GA) is the end-stage manifestation of atrophic age-related macular degeneration (AMD). The disease progresses slowly over time, eventually causing loss of central vision. Its cause and pathomechanism are not fully known. Previous studies have suggested that vitreoretinal traction (VRT) may contribute to the progression of neovascular AMD. The aim of this study was to...
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ژورنال
عنوان ژورنال: Retina
سال: 2016
ISSN: 0275-004X
DOI: 10.1097/iae.0000000000001258